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KMID : 0438219750120030723
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Korea University Medical Journal
1975 Volume.12 No. 3 p.723 ~ p.731
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Effect of Partial Ligation of the Abdominal Vena Cava on the Glomerular Filtration Rate
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Abstract
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Effect of Partial Ligation of the Abdominal Vena Cava
on the Glomerular Filtration Rate
Jeoung Ku Lee, M.D., Duck Syung Choi, M. D.
Department of Physiology, College of Medicine, Korea University, Seoul, Korea
Effect of partial ligation of the abdominal vena cava on the glomerular filtration rate (inulin clearance) was observed in 39 rabbits. Vena cava was ligated to one-half of the original lumen under nembutal anesthesia at the level just upper the right renal vein. Sixteen rabbits served as the control animal, 12 rabbits were observed 7 to 10 days after the partial ligation, 11 rabbits were observed 90 minutes after the partial ligation. Inulin clearance in the normal control rabbits was on average 2.171. 25 ml/min (MeanS. D. ) or 14.018.04 ml/min/mz. Inulin clearance decreased to 1.360.78 ml/min or 8.514. 14 ml/min/mZ in rabbits 7 to 10 days after the partial ligation. In 11 rabbits inulin clearance observed 90 minutes after ligation decreased markedly to 1.090. 50 ml/min or 7.003.31 ml/min/mz
Thus it was concluded that the partial ligation of abdominal vena cava at the level just upper the renal vein decreased the glomerular filtration rate.
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KEYWORD
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